Arthur S Tischler Selected Research

Succinate Dehydrogenase (Fumarate Reductase)

1/2020	Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas.
1/2020	A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/- rats.
6/2019	A Previously Unrecognized Monocytic Component of Pheochromocytoma and Paraganglioma.
11/2018	A unique model for SDH-deficient GIST: an endocrine-related cancer.
6/2015	SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T).
8/2013	Paragangliomas: update on differential diagnostic considerations, composite tumors, and recent genetic developments.
4/2013	Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas.
1/2013	Landscape of the mitochondrial Hsp90 metabolome in tumours.
1/2012	Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue.
7/2005	A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.

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Arthur S Tischler Research Topics

Disease

42	Neoplasms (Cancer) 12/2021 - 01/2003
32	Pheochromocytoma 01/2020 - 07/2002
14	Paraganglioma (Paragangliomas) 01/2020 - 02/2011
7	Neoplasm Metastasis (Metastasis) 03/2014 - 02/2007
5	Hypoxia (Hypoxemia) 01/2018 - 10/2002
3	Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis) 01/2020 - 07/2002
3	Multiple Endocrine Neoplasia Type 2a (MEN 2) 01/2020 - 10/2004
3	Hyperplasia 12/2017 - 01/2003
3	Neuroendocrine Tumors (Neuroendocrine Tumor) 02/2005 - 09/2004
3	Neurofibromatoses (Neurofibromatosis) 10/2002 - 07/2002
2	Neurofibromatosis 1 (Neurofibromatosis Type I) 02/2005 - 10/2004
1	Thyroid Neoplasms (Thyroid Cancer) 01/2020
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 11/2018
1	Islet cell tumor syndrome 12/2017
1	Primary Hyperparathyroidism 11/2017
1	Somatostatinoma 12/2016
1	Polycythemia (Erythrocytosis) 12/2016
1	Inborn Genetic Diseases (Disease, Hereditary) 08/2013
1	Disease Progression 01/2013
1	Carcinogenesis 01/2013
1	Extra-Adrenal Paraganglioma (Paraganglioma, Extra Adrenal) 03/2012
1	Pituitary Neoplasms (Pituitary Adenoma) 09/2011

Drug/Important Bio-Agent (IBA)

10	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2020 - 07/2005
10	CatecholaminesIBA 07/2017 - 07/2002
9	Proteins (Proteins, Gene)FDA Link 12/2017 - 01/2003
6	Adrenergic Agents (Adrenergic Drugs)IBA 01/2018 - 10/2002
5	EnzymesIBA 01/2020 - 07/2002
4	Chromogranin AIBA 09/2011 - 01/2003
3	Pharmaceutical PreparationsIBA 03/2021 - 01/2008
3	Biomarkers (Surrogate Marker)IBA 03/2021 - 03/2012
3	SynaptophysinIBA 06/2019 - 10/2004
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 03/2014 - 01/2003
3	Proto-Oncogene Proteins c-retIBA 01/2008 - 07/2002
2	Transcription Factors (Transcription Factor)IBA 12/2021 - 10/2002
2	Oxygen (Dioxygen)IBA 11/2018 - 01/2018
2	Myc associated factor XIBA 12/2017 - 11/2017
2	Biological ProductsIBA 03/2017 - 01/2009
2	endothelial PAS domain-containing protein 1IBA 12/2016 - 05/2013
2	Adenosine Triphosphate (ATP)IBA 01/2015 - 02/2013
2	LuciferasesIBA 01/2014 - 03/2012
2	DNA (Deoxyribonucleic Acid)IBA 05/2013 - 02/2005
2	Messenger RNA (mRNA)IBA 01/2012 - 01/2003
2	ChromograninsIBA 09/2011 - 10/2004
2	Phosphopyruvate Hydratase (Enolase)IBA 09/2011 - 10/2004
2	Phenylethanolamine N-MethyltransferaseIBA 01/2008 - 01/2003
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2008 - 01/2003
2	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 02/2005 - 07/2002
2	Chromogranin BIBA 10/2004 - 01/2003
1	Keratins (Keratin)IBA 12/2021
1	Glucagon (Glukagon)FDA Link 12/2021
1	Pancreatic Polypeptide (Pancreatic Polypeptide (PP))IBA 12/2021
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 01/2020
1	PolyaminesIBA 01/2020
1	4-carboxyphenylglyoxalIBA 01/2020
1	ProteomeIBA 06/2019
1	CD163 antigenIBA 06/2019
1	AntioxidantsIBA 11/2018
1	EnkephalinsIBA 01/2018
1	OMS 2017IBA 01/2018
1	fluorodopa F 18IBA 12/2017
1	Parathyroid Hormone (Parathormone)IBA 11/2017
1	ChromatesIBA 07/2017
1	Fixatives (Pickling Agents)IBA 07/2017
1	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 12/2016
1	Anesthetics (Anesthetic Agents)IBA 07/2015
1	AntibodiesIBA 01/2015
1	ResveratrolIBA 01/2015
1	AcidsIBA 01/2015
1	AurovertinsIBA 01/2015
1	Indicators and Reagents (Reagents)IBA 01/2015
1	AngiostatinsIBA 01/2015
1	Dopamine (Intropin)FDA LinkGeneric 03/2014
1	3-methoxytyramine (methoxytyramine)IBA 03/2014
1	CamptothecinIBA 01/2014
1	Azacitidine (5 Azacytidine)FDA Link 01/2014
1	Topoisomerase I InhibitorsIBA 01/2014
1	A-Form DNA (A-DNA)IBA 01/2014
1	Formaldehyde (Formol)FDA Link 05/2013
1	ParaffinIBA 05/2013
1	TOR Serine-Threonine KinasesIBA 02/2013
1	Mechanistic Target of Rapamycin Complex 2IBA 02/2013
1	Mechanistic Target of Rapamycin Complex 1IBA 02/2013
1	(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA 02/2013
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2013
1	Antineoplastic Agents (Antineoplastics)IBA 03/2012
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2012
1	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2012
1	Adrenocorticotropic Hormone (ACTH)FDA Link 09/2011
1	ProlactinIBA 09/2011
1	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 02/2011
1	Histone Deacetylases (Histone Deacetylase)IBA 02/2011
1	romidepsin (FK228)FDA Link 02/2011
1	Desipramine (Pertofrane)FDA LinkGeneric 02/2011
1	Reserpine (Serpasil)FDA Link 02/2011
1	Histone Deacetylase InhibitorsIBA 02/2011

Therapy/Procedure

7	Therapeutics 04/2013 - 01/2006
2	Thyroidectomy 01/2020 - 12/2005
1	Liver Transplantation 07/2015
1	Drug Therapy (Chemotherapy) 01/2014
1	Aftercare (After-Treatment) 02/2011